Diterpenes from the Genus Xylopia

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Diterpenes from Xylopia langsdorffiana inhibit cell growth and induce differentiation in human leukemia cells.

Two new diterpenes were isolated from stems and leaves of Xylopia langsdorffiana, ent-atisane-7alpha,16alpha-diol (xylodiol) and ent-7alpha-acetoxytrachyloban-18-oic acid (trachylobane), along with the known 8(17),12E,14-labdatrien-18-oic acid (labdane). We investigated their antitumour effects on HL60, U937 and K562 human leukemia cell lines. We found that xylodiol was the most potent diterpen...

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A new species of the lenticel fungal genus Claviradulomyces (Ostropales) from the Brazilian Atlantic forest tree Xylopia sericea (Annonaceae)

Claviradulomyces xylopiae sp. nov. is introduced for a fungus occurring in association with abnormal (enlarged, spongy) lenticels of Xylopia sericea (Annonaceae), a common tree of the Atlantic forest and Cerrado ecosystems in Brazil. This is the second species described in the genus and, although it is morphologically distinct from the type species, C. dabeicola from West Africa, it possesses t...

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Diterpenes from Erythroxylum barbatum

Das raízes de Erythroxylum barbatum foram isolados dois novos diterpenos entrosan-1ona-5α,15ξ,16-triol (1) e ent-11α-acetoxi-devadarano-15ξ,16-diol (2), além do ent-devadarano15ξ,16-diol (erythroxidiol X, 3) e do procesterol. Investigação do lenho do caule forneceu o ent-devadarano-11α,15ξ,16-triol (erythroxitriol Q, 4), o ent-devadarano-7β,15ξ,16-triol (hidroxidevadarool, 5), o β-sitosterol e ...

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Cembrane diterpenes from the gorgonian Leptogorgia laxa.

The new cembrane diterpenes leptodienone A (2) and leptodienone B (3) and the known compounds lopholide, lophodiol B, lophodione, and lophotoxin (1) have been isolated from the gorgonian Leptogorgia laxa collected in the Gulf of California. The structures of the new metabolites have been established by spectroscopic techniques. The in vitro cytotoxicity of the new compounds has been tested agai...

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Diterpenes from the leaves of Croton zambesicus.

Two new trachylobane- and one isopimarane-type diterpenoids: ent-18-hydroxy-trachyloban-3-one; ent-trachyloban-3-one; isopimara-7,15-dien-3beta-ol, were isolated from the leaves of Croton zambesicus, together with trans-phytol, beta-sitosterol, alpha-amyrin and stigmasterol. The structures were determined by extensive NMR techniques and X-ray analysis. The cytotoxicity of these compounds has be...

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ژورنال

عنوان ژورنال: Revista Virtual de Química

سال: 2017

ISSN: 1984-6835

DOI: 10.21577/1984-6835.20170099